Asexual blood-stage malaria vaccine development: facing the challenges
B Genton, ZH Reed - Current Opinion in Infectious Diseases, 2007 - journals.lww.com
B Genton, ZH Reed
Current Opinion in Infectious Diseases, 2007•journals.lww.comConsiderable efforts and funding are available to shift from laboratory experiments to field
trials. Field trials remain the definitive method to assess the real impact of different vaccines
in the target populations. More rigorous side-by-side comparisons are needed between the
different vaccines using standardized in-vitro and in-vivo testing, so that the most promising
candidates will be selected for further development.
trials. Field trials remain the definitive method to assess the real impact of different vaccines
in the target populations. More rigorous side-by-side comparisons are needed between the
different vaccines using standardized in-vitro and in-vivo testing, so that the most promising
candidates will be selected for further development.
Summary
Considerable efforts and funding are available to shift from laboratory experiments to field trials. Field trials remain the definitive method to assess the real impact of different vaccines in the target populations. More rigorous side-by-side comparisons are needed between the different vaccines using standardized in-vitro and in-vivo testing, so that the most promising candidates will be selected for further development.
Lippincott Williams & Wilkins