Multiple microsample analysis of intratumor estrogen receptor distribution in breast cancers by a combined biochemical/immunohistochemical method
JP van Netten, IG Thornton, SJ Carlyle… - European Journal of …, 1987 - Elsevier
A multiple microsample analysis of estrogen receptors (ER) was performed on 81 samples
obtained from 21 human breast cancers using a biochemical (BC) and
immunohistochemical (IHC) method. Qualitative agreement occurred in 96% of the cases.
Using both the percentage of cells staining specifically for ER as well as the intensity of
staining (Histoscore) a semiquantitative correlation between the two analyses was obtained.
Large variations in cellularity and the percentage of cells that stained specifically for ER …
obtained from 21 human breast cancers using a biochemical (BC) and
immunohistochemical (IHC) method. Qualitative agreement occurred in 96% of the cases.
Using both the percentage of cells staining specifically for ER as well as the intensity of
staining (Histoscore) a semiquantitative correlation between the two analyses was obtained.
Large variations in cellularity and the percentage of cells that stained specifically for ER …