[HTML][HTML] miR-372 regulates cell cycle and apoptosis of ags human gastric cancer cell line through direct regulation of LATS2

WJ Cho, JM Shin, JS Kim, MR Lee, KS Hong, JH Lee… - Molecules and cells, 2009 - Elsevier
Previously, we have reported tissue-and stage-specific expression of miR-372 in human
embryonic stem cells and so far, not many reports speculate the function of this mi-croRNA
(miRNA). In this study, we screened various human cancer cell lines including gastric cancer
cell lines and found first time that miR-372 is expressed only in AGS human gastric
adenocarcinoma cell line. Inhibition of miR-372 using antisense miR-372 oligonucleotide
(AS-miR-372) suppressed proliferation, arrested the cell cycle at G2/M phase, and increased …