Experimental design and low-level analysis of microarray data
BM Bolstad, F Collin, KM Simpson, RA Irizarry… - International review of …, 2004 - Elsevier
Publisher Summary This chapter reviews the design and low-level analysis of microarray
experiments. Microarray experiments are used to quantify and compare gene expression on
a large scale. Such experiments can be costly in terms of equipment, consumables, and
time. Thus, careful design is important. Low-level analysis is carried out between the image
analysis phase and interrogation of gene expression data. The goal of low-level analysis is
to take raw data from the scanner, without any biological interpretation, and process it to …
experiments. Microarray experiments are used to quantify and compare gene expression on
a large scale. Such experiments can be costly in terms of equipment, consumables, and
time. Thus, careful design is important. Low-level analysis is carried out between the image
analysis phase and interrogation of gene expression data. The goal of low-level analysis is
to take raw data from the scanner, without any biological interpretation, and process it to …