Receptors for the anaphylatoxins C3a and C5a are expressed in human atherosclerotic coronary plaques
R Oksjoki, P Laine, S Helske, P Vehmaan-Kreula… - Atherosclerosis, 2007 - Elsevier
The anaphylatoxins C3a and C5a are potent chemotactic and pro-inflammatory peptides
that are released during complement activation, and recent clinical work have suggested
them a role in acute coronary events. Here we studied whether human coronary plaques
express anaphylatoxin receptors C3aR and C5aR, ie whether they have the potential to
respond to anaphylatoxins. For this purpose, both normal (n= 14) and atherosclerotic (n= 20)
human coronary artery samples were collected for histological and PCR analyses …
that are released during complement activation, and recent clinical work have suggested
them a role in acute coronary events. Here we studied whether human coronary plaques
express anaphylatoxin receptors C3aR and C5aR, ie whether they have the potential to
respond to anaphylatoxins. For this purpose, both normal (n= 14) and atherosclerotic (n= 20)
human coronary artery samples were collected for histological and PCR analyses …