Evaluation of pathologic criteria for acute renal allograft rejection: reproducibility, sensitivity, and clinical correlation.

RB Colvin, AH Cohen, C Saiontz… - Journal of the …, 1997 - journals.lww.com
This study was designed to evaluate the pathologic criteria used for acute renal allograft
rejection that were developed by a panel of renal pathologists participating in the
Cooperative Clinical Trials in Transplantation, a National Institutes of Health-supported,
multicenter research group. The panel defined three categories of acute rejection.(1) Type I:
mononuclear infiltrate in> or= 5% of cortex, a total of at least three tubules with tubulitis in 10
consecutive high-power fields from the most severely affected areas, and at least two of the …