Positron emission tomography scanning: current and future applications

J Czernin, ME Phelps - Annual review of medicine, 2002 - annualreviews.org
J Czernin, ME Phelps
Annual review of medicine, 2002annualreviews.org
▪ Abstract Whole-body positron emission tomography (PET) imaging with 18F deoxyglucose
(FDG) is a molecular imaging modality that detects metabolic alterations in tumor cells that
are common to neoplastic cells. FDG-PET has recently been approved by the Health Care
Finance Administration for Medicare reimbursement for diagnosing, staging, and restaging
lung cancer, colorectal cancer, lymphoma, melanoma, head and neck cancer, and
esophageal cancer. This review discusses the scientific evidence that led to the emergence …
Abstract
Whole-body positron emission tomography (PET) imaging with 18F deoxyglucose (FDG) is a molecular imaging modality that detects metabolic alterations in tumor cells that are common to neoplastic cells. FDG-PET has recently been approved by the Health Care Finance Administration for Medicare reimbursement for diagnosing, staging, and restaging lung cancer, colorectal cancer, lymphoma, melanoma, head and neck cancer, and esophageal cancer. This review discusses the scientific evidence that led to the emergence of PET imaging as an accepted clinical tool in patients with solitary pulmonary nodules, lung cancer, colorectal cancer, melanoma, lymphoma, breast cancer, and other cancers. When possible, we compare the performance of PET to that of anatomical imaging. We discuss future clinical applications of this imaging modality.
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