[HTML][HTML] An appraisal of tolerance in liver transplantation
J Lerut, A Sanchez-Fueyo - American journal of transplantation, 2006 - Elsevier
Human liver allografts have a lower susceptibility to rejection than other organs. In addition,
in some liver transplant recipients immunosuppressive drugs can be completely withdrawn,
and these patients are considered as´ operationally´ tolerant. Careful scrutiny of
accumulated clinical experience indicates that elective immunosuppressive drug weaning is
feasible in almost 20% of selected liver transplant recipients. This is associated with an
incidence of 12% to 76% of acute cellular rejection, but these episodes are commonly mild …
in some liver transplant recipients immunosuppressive drugs can be completely withdrawn,
and these patients are considered as´ operationally´ tolerant. Careful scrutiny of
accumulated clinical experience indicates that elective immunosuppressive drug weaning is
feasible in almost 20% of selected liver transplant recipients. This is associated with an
incidence of 12% to 76% of acute cellular rejection, but these episodes are commonly mild …