[HTML][HTML] Insights into programmed cell death through structural biology

SW Fesik - Cell, 2000 - cell.com
Cell, 2000cell.com
Programmed cell death plays a critical role in controlling the number of cells in development
and throughout an organism's life by the removal of cells at the appropriate time. It is an
important biological process for the elimination of unwanted cells such as those with
potentially harmful genomic mutations, autoreactive lymphocytes, or virally infected cells.
Alterations of this normal process can result in the disruption of the delicate balance
between cell proliferation and cell death and can lead to a variety of diseases (
Programmed cell death plays a critical role in controlling the number of cells in development and throughout an organism's life by the removal of cells at the appropriate time. It is an important biological process for the elimination of unwanted cells such as those with potentially harmful genomic mutations, autoreactive lymphocytes, or virally infected cells. Alterations of this normal process can result in the disruption of the delicate balance between cell proliferation and cell death and can lead to a variety of diseases (
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