Asymptomatic hyperuricemia. Risks and consequences in the Normative Aging Study

EW Campion, RJ Glynn, LO Delabry - The American journal of medicine, 1987 - Elsevier
To quantify the consequences of asymptomatic hyperuricemia, this study examined rates for
a first episode of gouty arthritis based on 30,147 human-years of prospective observation. A
cohort of 2,046 initially healthy men in the Normative Aging Study was followed for 14.9
years with serial examinations and measurement of urate levels. With prior serum urate
levels of 9 mg/dl or more, the annual incidence rate of gouty arthritis was 4.9 percent,
compared with 0.5 percent for urate levels of 7.0 to 8.9 mg/dl and 0.1 percent for urate levels …