The induction of the acrosome reaction in guinea-pig sperm by the divalent metal cation ionophore A23187
DPL Green - Journal of Cell Science, 1978 - journals.biologists.com
DPL Green
Journal of Cell Science, 1978•journals.biologists.comThe divalent metal cation, ionophore A23187 induces an acrosome reaction in guinea-pig
sperm which is dependent on external calcium. Examination of this acrosome reaction by
electron microscopy shows that it is morphologically normal. The known properties of
A23187 and the morphological similarity between the acrosome reaction and the secretory
discharges of other secretory cells suggests that the immediate cause of the acrosome
reaction is an increase in the cytoplasmic free calcium concentration.
sperm which is dependent on external calcium. Examination of this acrosome reaction by
electron microscopy shows that it is morphologically normal. The known properties of
A23187 and the morphological similarity between the acrosome reaction and the secretory
discharges of other secretory cells suggests that the immediate cause of the acrosome
reaction is an increase in the cytoplasmic free calcium concentration.
Abstract
The divalent metal cation, ionophore A23187 induces an acrosome reaction in guinea-pig sperm which is dependent on external calcium. Examination of this acrosome reaction by electron microscopy shows that it is morphologically normal. The known properties of A23187 and the morphological similarity between the acrosome reaction and the secretory discharges of other secretory cells suggests that the immediate cause of the acrosome reaction is an increase in the cytoplasmic free calcium concentration.
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