Study on the activation of phospholipases A2 by purinergic agonists in rat submandibular ductal cells
E Kabre, N Chaı̈b, P Boussard, G Merino… - … et Biophysica Acta (BBA …, 1999 - Elsevier
Extracellular ATP and benzoyl-ATP (Bz-ATP) increased the release of [3H] arachidonic acid
([3H] AA) from prelabeled rat submandibular gland (RSMG) ductal cells respectively two-and
threefold. Both agonists also increased the release of [3H] AA from acini but at a lower level
(+ 50% and+ 100% respectively). Carbachol had no significant effect on either cellular
population. In ductal cells phorbol myristate acetate, an activator of protein kinase C, slightly
increased the basal release of [3H] AA but did not affect the release of [3H] AA in response …
([3H] AA) from prelabeled rat submandibular gland (RSMG) ductal cells respectively two-and
threefold. Both agonists also increased the release of [3H] AA from acini but at a lower level
(+ 50% and+ 100% respectively). Carbachol had no significant effect on either cellular
population. In ductal cells phorbol myristate acetate, an activator of protein kinase C, slightly
increased the basal release of [3H] AA but did not affect the release of [3H] AA in response …