Bicarbonate secretion: a neglected aspect of colonic ion transport
HJ Binder, V Rajendran, V Sadasivan… - Journal of clinical …, 2005 - journals.lww.com
Understanding of the mechanism of colonic electrolyte transport has markedly increased
over the past three decades. This article provides a brief summary of the critical features of
Na, Cl, and K transport in the large intestine and how these processes may be altered in
diarrhea. Less understood is the mechanism of colonic HCO 3 secretion. Recent progress in
the regulation of HCO 3 secretion in the distal colon is summarized with emphasis on the
interrelationship between Cl-dependent, short-chain fatty acid (SCFA)-dependent, and …
over the past three decades. This article provides a brief summary of the critical features of
Na, Cl, and K transport in the large intestine and how these processes may be altered in
diarrhea. Less understood is the mechanism of colonic HCO 3 secretion. Recent progress in
the regulation of HCO 3 secretion in the distal colon is summarized with emphasis on the
interrelationship between Cl-dependent, short-chain fatty acid (SCFA)-dependent, and …