[CITATION][C] Werner syndrome: molecular genetics and mechanistic hypotheses
RJ Monnat Jr - Experimental gerontology, 1992 - Elsevier
WERNER SYNDROME (WS; McKusick catalog no. 27770) has held a particular fascination
for biologists and physicians interested in human aging and the mechanisms that control it.
The most intriguing aspect of this uncommon autosomal recessive disease is the
appearance in young adults of features reminiscent of premature aging. The WS phenotype
includes several ominous age-dependent disease processes (eg, the development of
neoplasia and cardiovascular disease), as well as a number of the medically less important …
for biologists and physicians interested in human aging and the mechanisms that control it.
The most intriguing aspect of this uncommon autosomal recessive disease is the
appearance in young adults of features reminiscent of premature aging. The WS phenotype
includes several ominous age-dependent disease processes (eg, the development of
neoplasia and cardiovascular disease), as well as a number of the medically less important …