Over the past decade, rapid, high‐sensitivity mass spectrometric strat‐egies have been
developed and optimized for screening for the types of N‐and O‐glycans present in a
diverse range of biological material, including secretions, cell lines, tissues, and organs.
These glycomic strategies are based on matrix‐assisted laser desorption/ionization (MALDI)
time‐of‐flight mass fingerprinting of permethylated derivatives, combined with electrospray
(ES) or MALDI tandem mass spectrometry (MS/MS) sequencing and gas chromatography …