Analysis of effector mechanisms in murine cardiac allograft rejection
DZ Alexander, TC Pearson, R Hendrix, SC Ritchie… - Transplant …, 1996 - Elsevier
Multiple effector cells have been implicated in transplant rejection, including cytotoxic T
cells, B cells, macrophages and NK cells. 1 The purpose of this study was to examine the
effector pathways which are critical to murine cardiac allograft rejection. RT-PCR (reverse
transcriptase-polymerase chain reaction) analysis of syngeneic and allogeneic vascularized
heterotopic cardiac grafts at 5, 8 and 12 days following transplantation demonstrate
constitutive expression of Fas in both the syngeneic and allogeneic grafts as well as in …
cells, B cells, macrophages and NK cells. 1 The purpose of this study was to examine the
effector pathways which are critical to murine cardiac allograft rejection. RT-PCR (reverse
transcriptase-polymerase chain reaction) analysis of syngeneic and allogeneic vascularized
heterotopic cardiac grafts at 5, 8 and 12 days following transplantation demonstrate
constitutive expression of Fas in both the syngeneic and allogeneic grafts as well as in …