Primary immunodeficiency diseases: an update from the international union of immunological societies primary immunodeficiency diseases classification committee …
Although relatively rare, primary immunodeficiency diseases (PIDs) provide an excellent
window into the functioning of the immune system. In the late 1960s, observations on these
diseases, with their associated infections and genetics, bisected the immune system into
humoral immunity and cell-mediated immunity. These diseases also represent a challenge
in their diagnosis and treatment. Beginning in 1970, a unified nomenclature for the then-
known PIDs was created by a committee convoked by the World Health Organization. Since …
window into the functioning of the immune system. In the late 1960s, observations on these
diseases, with their associated infections and genetics, bisected the immune system into
humoral immunity and cell-mediated immunity. These diseases also represent a challenge
in their diagnosis and treatment. Beginning in 1970, a unified nomenclature for the then-
known PIDs was created by a committee convoked by the World Health Organization. Since …