Kaposi sarcoma in transplantation

C Lebbé, C Legendre, C Francès - Transplantation Reviews, 2008 - Elsevier
Kaposi sarcoma (KS) is a multicentric neoplasm of lymphatic endothelium derived cells
infected with Kaposi's human herpesvirus 8 (HHV8). Post-transplant KS can lead to
multifocal, progressive (florid) lesions with frequent primary involvement of the oral mucosa
and dissemination to the viscera. KS prevalence after organ transplantation varies greatly
depending on the prevalence of HHV8 infection in the general population. Most cases of
post-transplant KS develop as a result of viral reactivation. Immunohistochemistry using a …