[HTML][HTML] Vascular endothelial growth factor-C stimulates the migration and proliferation of Kaposi's sarcoma cells

S Marchio, L Primo, M Pagano, G Palestro… - Journal of Biological …, 1999 - ASBMB
Recent evidence suggesting vascular endothelial growth factor-C (VEGF-C), which is a
regulator of lymphatic and vascular endothelial development, raised the question whether
this molecule could be involved in Kaposi's sarcoma (KS), a strongly angiogenic and
inflammatory tumor often associated with infection by human immunodeficiency virus-1. This
disease is characterized by the presence of a core constituted of three main populations of"
spindle" cells, having the features of lymphatic/vascular endothelial cells …