Kaposi's sarcoma: a result of the interplay among inflammatory cytokines, angiogenic factors and viral agents

B Ensoli, M Stürzl - Cytokine & growth factor reviews, 1998 - Elsevier
Kaposi's sarcoma (KS) is an angioproliferative disease occurring in 4 clinic-epidemiologic
forms. Although the AIDS-associated KS (AIDS-KS) is the most aggressive, all forms of KS
share the same immunological and histopathological features suggesting common
etiological and pathogenic factors. Recent data indicate that at least in early stage KS is not
a real sarcoma but an angio-hyperplastic-inflammatory lesion mediated by inflammatory
cytokines and angiogenic factors, that is triggered or amplified by infection with human …