Polyovular follicles associated with human in vitro fertilization

PV Dandekar, MC Martin, RH Glass - Fertility and sterility, 1988 - Elsevier
Polyovular follicles were found in 61 (24%) of 251 laparoscopies performed for in vitro
fertilization. Of 898 follicles that contained at least one oocyte, 76 (8%) were polyovular.
When the oocytes from polyovular follicles were assessed by morphologic criteria, it was
found that 46 of the follicles contained oocytes that were discordant in maturity. Thus,
oocytes can develop at different rates even though they are exposed to the same follicular
fluid. It is possible that the microenvironment provided by the cellular investments of oocytes …