[PDF][PDF] Membrane biogenesis: networking at the ER with atlastin
H Farhan, HP Hauri - Current biology, 2009 - cell.com
H Farhan, HP Hauri
Current biology, 2009•cell.comThe peripheral endoplasmic reticulum forms a dynamic network of interconnected
membrane tubules. Although some determinants of this striking architecture are known, the
mechanism underlying fusion of individual tubules has remained elusive. Two studies now
identify atlastin proteins as key mediators of homotypic fusion of endoplasmic reticulum
membranes.
membrane tubules. Although some determinants of this striking architecture are known, the
mechanism underlying fusion of individual tubules has remained elusive. Two studies now
identify atlastin proteins as key mediators of homotypic fusion of endoplasmic reticulum
membranes.
Summary
The peripheral endoplasmic reticulum forms a dynamic network of interconnected membrane tubules. Although some determinants of this striking architecture are known, the mechanism underlying fusion of individual tubules has remained elusive. Two studies now identify atlastin proteins as key mediators of homotypic fusion of endoplasmic reticulum membranes.
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