Properties of monoclonal antibodies to mouse Ig allotypes, H-2, and Ia antigens
VT Oi, PP Jones, JW Goding, LA Herzenberg… - … of Tumors of T and B …, 1979 - Springer
VT Oi, PP Jones, JW Goding, LA Herzenberg, LA Herzenberg
Lymphocyte Hybridomas: Second Workshop on “Functional Properties of Tumors of …, 1979•SpringerAdvances in somatic cell hybridization techniques have made it possible to generate hybrid
cell lines producing monospecific antibodies directed at desired antigenic determinants (1).
In this paper a modification of the cell fusion procedure (2, 3) was used to recover stable
hybrid cell lines secreting IgG antibodies to:(a) mouse major histocompatibility complex
(MHC) alloantigens (H-2K and IA); and (b) mouse immunoglobulin (Ig) allotypes (Ig-1b, Ig-
5a, and Ig-5b).
cell lines producing monospecific antibodies directed at desired antigenic determinants (1).
In this paper a modification of the cell fusion procedure (2, 3) was used to recover stable
hybrid cell lines secreting IgG antibodies to:(a) mouse major histocompatibility complex
(MHC) alloantigens (H-2K and IA); and (b) mouse immunoglobulin (Ig) allotypes (Ig-1b, Ig-
5a, and Ig-5b).
Abstract
Advances in somatic cell hybridization techniques have made it possible to generate hybrid cell lines producing monospecific antibodies directed at desired antigenic determinants (1). In this paper a modification of the cell fusion procedure (2,3) was used to recover stable hybrid cell lines secreting IgG antibodies to: (a) mouse major histocompatibility complex (MHC) alloantigens (H-2K and I-A); and (b) mouse immunoglobulin (Ig) allotypes (Ig-1b, Ig-5a, and Ig-5b).
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