Hypocretin (orexin) deficiency in human narcolepsy
The Lancet, 2000•thelancet.com
Hypocretin (orexin) deficiency in human narcolepsy - The Lancet Skip to Main Content
Advertisement The Lancet Journal Submit Article Log in Register Log in Submit Article Log
in Subscribe Skip menu This journal Read Online first Current issue All issues Special
issues Series Commissions About About the journal Alerts Request institutional access
External Link Multimedia Podcasts External Link Journals Journals The Lancet The Lancet
Child & Adolescent Health The Lancet Diabetes & Endocrinology The Lancet Digital Health …
Advertisement The Lancet Journal Submit Article Log in Register Log in Submit Article Log
in Subscribe Skip menu This journal Read Online first Current issue All issues Special
issues Series Commissions About About the journal Alerts Request institutional access
External Link Multimedia Podcasts External Link Journals Journals The Lancet The Lancet
Child & Adolescent Health The Lancet Diabetes & Endocrinology The Lancet Digital Health …
Summary
Alterations in the hypocretin receptor 2 and preprohypocretin genes produce narcolepsy in animal models. Hypocretin was undetectable in seven out of nine people with narcolepsy, indicating abnormal hypocretin transmission.
thelancet.com