[HTML][HTML] Regulation of vesicle trafficking in madin-darby canine kidney cells by Rab11a and Rab25

X Wang, R Kumar, J Navarre, JE Casanova… - Journal of Biological …, 2000 - ASBMB
Polarized epithelial cells maintain the polarized distribution of basolateral and apical
membrane proteins through a process of receptor-mediated endocytosis, sorting, and then
recycling to the appropriate membrane domain. We have previously shown that the small
GTP-binding proteins, Rab11a and Rab25, are associated with the apical recycling system
of Madin-Darby canine kidney cells. Here we have utilized inducible expression of wild-type,
dominant negative, and constitutively active mutants to directly compare the functions of …