The MEN II syndromes and the role of the ret proto-oncogene
BAJ Ponder, D Smith - Advances in cancer research, 1996 - Elsevier
Publisher Summary This chapter focuses on genetic and biological aspects of the multiple
endocrine neoplasia type II (MEN II) syndromes and of ret mutations. The discussion of
clinical and pathological aspects is limited for providing the background to the biological
problem and indicating the application of the genetic results. The MEN II syndromes are
dominantly inherited syndromes of tumor formation and disordered development that involve
principally four tissues: the “C” cells of the thyroid, the adrenal medulla, the parathyroid, and …
endocrine neoplasia type II (MEN II) syndromes and of ret mutations. The discussion of
clinical and pathological aspects is limited for providing the background to the biological
problem and indicating the application of the genetic results. The MEN II syndromes are
dominantly inherited syndromes of tumor formation and disordered development that involve
principally four tissues: the “C” cells of the thyroid, the adrenal medulla, the parathyroid, and …