A tutorial on the diffusibility and reactivity of free nitric oxide
JR Lancaster Jr - Nitric oxide, 1997 - Elsevier
In this review, I consider the quantitative consequences of the diffusion of free NO in
determining its biological actions. Several studies have measured the extent to which NO
diffuses away from an NO-producing cell, and the distance of its diffusion is quite large, on
the order of 100–200 μm. This wide diffusibility is consistent also with the high value for its
diffusion constant, 3300 μm2/s. Mathematical simulations based on this wide diffusibility
suggest that, within spatial limits of approximately 0.3–0.4 mm, the actions of free NO are …
determining its biological actions. Several studies have measured the extent to which NO
diffuses away from an NO-producing cell, and the distance of its diffusion is quite large, on
the order of 100–200 μm. This wide diffusibility is consistent also with the high value for its
diffusion constant, 3300 μm2/s. Mathematical simulations based on this wide diffusibility
suggest that, within spatial limits of approximately 0.3–0.4 mm, the actions of free NO are …