We review recent data on the plasticity of dorsal root ganglion (DRG) neurons as revealed
during cultivation in vitro. Some experiments on cultured developing DRG neurons and on
adult DRG neurons in vivo are also mentioned. Cultured developing and adult DRG neurons
can be switched from an apolar to a multipolar phenotype by fetal calf serum or fibronectin.
The effect is concentration dependent and occurs through an early modification of cell-
substratum interaction. Adult DRG neurons synthesize and release within hours after injury …