Cell cycle signaling and cardiovascular disease
EG Nabel, M Boehm, LM Akyurek… - Cold Spring Harbor …, 2002 - symposium.cshlp.org
EG Nabel, M Boehm, LM Akyurek, T Yoshimoto, MF Crook, M Olive, H San, X Qu
Cold Spring Harbor symposia on quantitative biology, 2002•symposium.cshlp.orgFigure 1. Cell cycle pathways. Mitogen-dependent progression through G1 phase and
initiation of S phase during the mammalian cell cycle are cooperatively regulated by the
cyclin-dependent kinases (CDKs) whose activities are controlled by CDK inhibitors (CKIs).
CKIs have been assigned to two families on the basis of their structure: the INK4 proteins
(p15, p16, p18, p19) and the CIP/KIP proteins (p21, p27, p57).(Reprinted, with permission,
from Nabel 2002 [copyright Macmillan] http://www. nature. com.)
initiation of S phase during the mammalian cell cycle are cooperatively regulated by the
cyclin-dependent kinases (CDKs) whose activities are controlled by CDK inhibitors (CKIs).
CKIs have been assigned to two families on the basis of their structure: the INK4 proteins
(p15, p16, p18, p19) and the CIP/KIP proteins (p21, p27, p57).(Reprinted, with permission,
from Nabel 2002 [copyright Macmillan] http://www. nature. com.)
Figure 1. Cell cycle pathways. Mitogen-dependent progression through G1 phase and initiation of S phase during the mammalian cell cycle are cooperatively regulated by the cyclin-dependent kinases (CDKs) whose activities are controlled by CDK inhibitors (CKIs). CKIs have been assigned to two families on the basis of their structure: the INK4 proteins (p15, p16, p18, p19) and the CIP/KIP proteins (p21, p27, p57).(Reprinted, with permission, from Nabel 2002 [copyright Macmillan] http://www. nature. com.)
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