The human immunoglobulin VH repertoire

GP Cook, IM Tomlinson - Immunology today, 1995 - Elsevier
A complete map of the human immunoglobulin VH locus on hromosome 14 has recently
been constructed. The locus is 1100kb in length and contains 51 functional VH segments
interspersed amongst a similar number of pseudogenes. Here, Graham Cook and Ian
Tomlinson review the organization of the locus, its polymorphism and the repertoire it
encodes.