Tumor hypoxia adversely affects the prognosis of carcinoma of the head and neck

DM Brizel, GS Sibley, LR Prosnitz, RL Scher… - International Journal of …, 1997 - Elsevier
Purpose: Tumor hypoxia adversely affects short term clinical radiation response of head and
neck cancer lymph node metastases and long term disease-free survival (DFS) in cervix
carcinoma. This study was performed to evalaute the relationship between tumor hypoxia
and DFS in patients with squamous carcinoma of th ehead and neck (SCCHN). Methods
and Materials: Pretreatment tumor pO2 was assessed polagographically in SCCHN patients.
All patients were AJCC Stage IV and had pretreatment oxygen measureemnt taken from …