T-type calcium channels in differentiation and proliferation

P Lory, I Bidaud, J Chemin - Cell calcium, 2006 - Elsevier
Low-voltage activated, T-type calcium channels (T-channels) are expressed in many
developing tissues and may be important in regulating important cellular phenotype
transitions leading to cell proliferation, differentiation, growth and death. The purpose of this
review is to relate and delineate the current data on the involvement of T-channels in
differentiation and proliferation. Owing to the recent cloning of the CaV3. 1, CaV3. 2 and
CaV3. 3 subunits coding for T-channels, classical electrophysiological and pharmacological …