In a separate paper, we developed a mathematical model describing HIV infection and used
it to suggest experiments for quantifying characteristic viral parameters. In this paper we
generalize the model to any well-mixed assay system. We also present complete and
rigorous derivations of fundamental results needed for the design and analysis of HIV
infectivity assays. The model is applicable to infectious agents with multiple receptors for
their target cell (eg HIV, Epstein-Barr virus and Plasmodium), and to blockers (both …