Vascular origin determines plasminogen activator expression in human endothelial cells: Renal endothelial cells produce large amounts of single chain urokinase …

J Wojta, RL Hoover, TO Daniel - Journal of Biological Chemistry, 1989 - ASBMB
Positioned at the boundary between intra-and extravascular compartments, endothelial cells
may influence many processes through their production of plasminogen activators (PA).
Available data have shown that tissue-type plasminogen activator (t-PA) is the major form
produced by human endothelial cells. We have compared the molecular forms of PA
produced by human endothelial cells from different microvascular and large vessel sources
including two different sites within the circulation of the kidney. Using combined …