The association of polycythemia with a cerebellar hemangioblastoma: The production of an erythropoiesis stimulating factor by the tumor
TA Waldmann, EH Levin, M Baldwin - The American Journal of Medicine, 1961 - Elsevier
A patient with associated cerebellar hemangioblastoma and polycythemia is presented. The
circulating red cell volume was increased to 44 cc. per kg., the plasma volume was within
normal limits. The apparent Gr 51 red cell life span (T 1 2) was twenty-six days. The plasma
iron turnover and red cell iron turnover were accelerated to 0.47 and 0.44 mg. per kg. per
day, respectively, indicating increased red cell synthesis. There was normal incorporation
and release of Fe 59 over the sacral marrow on body surface counting indicating red cell …
circulating red cell volume was increased to 44 cc. per kg., the plasma volume was within
normal limits. The apparent Gr 51 red cell life span (T 1 2) was twenty-six days. The plasma
iron turnover and red cell iron turnover were accelerated to 0.47 and 0.44 mg. per kg. per
day, respectively, indicating increased red cell synthesis. There was normal incorporation
and release of Fe 59 over the sacral marrow on body surface counting indicating red cell …