Apolipoprotein E (apoE) is the primary recognition signal on triglyceride-rich lipoproteins
responsible for interacting with low density lipoprotein (LDL) receptors and LDL receptor-
related protein (LRP). It has been shown that lipoprotein lipase (LPL) and hepatic
triglyceride lipase (HTGL) promote receptor-mediated uptake and degradation of very low
density lipoproteins (VLDL) and remnant particles, possibly by directly binding to lipoprotein
receptors. In this study we have investigated the requirement for apoE in lipase-stimulated …