[HTML][HTML] A Novel Cytochrome P450 Expressed Primarily in Brain (∗)

G Stapleton, M Steel, M Richardson, JO Mason… - Journal of Biological …, 1995 - ASBMB
hct-1 (hippocampal transcript) was detected in a differential screen of a rat hippocampal
cDNA library. Expression of hct-1 was enriched in the formation but was also detected in rat
liver and kidney, though at much lower levels; expression was barely detectable in testis,
ovary, and adrenal. In liver, unlike brain, expression was sexually dimorphic; hepatic
expression was greatly reduced in female rats. In mouse, brain expression was widespread,
with the highest levels being detected in corpus callosum; only low levels were detected in …