Ultrastructural study on kidney cell injury following various types of shock in 26 immediate autopsy patients.
T Sato, Y Kamiyama, RT Jones, RA Cowley… - Advances in Shock …, 1978 - europepmc.org
T Sato, Y Kamiyama, RT Jones, RA Cowley, BF Trump
Advances in Shock Research, 1978•europepmc.orgIn acute renal failure in man following shock and trauma, an amazing discrepancy was
found between the complete breakdown of renal function and the very modest histological
and ultrastructural changes in" immediate autopsy" patients, even in those who sustained
septic shock. Although, from this limited number of studies no satisfactory interpretation of
the pathogenesis of acute renal failure can be deduced from the structural changes found,
the findings do indicate that hypoxia plays a key role in aggravating the structural changes …
found between the complete breakdown of renal function and the very modest histological
and ultrastructural changes in" immediate autopsy" patients, even in those who sustained
septic shock. Although, from this limited number of studies no satisfactory interpretation of
the pathogenesis of acute renal failure can be deduced from the structural changes found,
the findings do indicate that hypoxia plays a key role in aggravating the structural changes …
In acute renal failure in man following shock and trauma, an amazing discrepancy was found between the complete breakdown of renal function and the very modest histological and ultrastructural changes in" immediate autopsy" patients, even in those who sustained septic shock. Although, from this limited number of studies no satisfactory interpretation of the pathogenesis of acute renal failure can be deduced from the structural changes found, the findings do indicate that hypoxia plays a key role in aggravating the structural changes that induce permanent cell damage in man following shock of various etiologies including septic shock.
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