[HTML][HTML] Mucus secretion from single submucosal glands of pig: stimulation by carbachol and vasoactive intestinal peptide
Secretion rates of> 700 individual glands in isolated tracheal mucosa from 56 adult pigs
were monitored optically." Basal" secretion of 0.7±0.1 nl· min− 1 gland− 1 was observed 1–9
h post-harvest but was near zero on day 2. Secretion to carbachol (10 μm) peaked at 2–3
min and then declined to a sustained phase. Peak secretion was 12.4±1.1 nl· min− 1 gland−
1; sustained secretion was approximately one-third of peak secretion. Thapsigargin (1 μm)
increased secretion from 0.1±0.05 to 0.7±0.2 nl· min− 1 gland− 1; thapsigargin did not cause …
were monitored optically." Basal" secretion of 0.7±0.1 nl· min− 1 gland− 1 was observed 1–9
h post-harvest but was near zero on day 2. Secretion to carbachol (10 μm) peaked at 2–3
min and then declined to a sustained phase. Peak secretion was 12.4±1.1 nl· min− 1 gland−
1; sustained secretion was approximately one-third of peak secretion. Thapsigargin (1 μm)
increased secretion from 0.1±0.05 to 0.7±0.2 nl· min− 1 gland− 1; thapsigargin did not cause …