Variant antigen expression in malaria infections: posttranscriptional gene silencing, virulence and severe pathology
MR Galinski, V Corredor - Molecular and biochemical parasitology, 2004 - Elsevier
This review highlights features of two simian malarias, Plasmodium knowlesi and
Plasmodium coatneyi, that make them attractive models for investigations relating to the
molecular mechanisms governing antigenic variation and the development of human
pathology in Plasmodium falciparum infections. This paper also reflects our current
conclusions and working hypotheses as presented at the Severe Malaria meeting in
November 2002 at the Karolinska Institute in Sweden. We propose that the 3 regions of the …
Plasmodium coatneyi, that make them attractive models for investigations relating to the
molecular mechanisms governing antigenic variation and the development of human
pathology in Plasmodium falciparum infections. This paper also reflects our current
conclusions and working hypotheses as presented at the Severe Malaria meeting in
November 2002 at the Karolinska Institute in Sweden. We propose that the 3 regions of the …