Sustained increases in numbers of pulmonary dendritic cells after respiratory syncytial virus infection
M Beyer, H Bartz, K Hörner, S Doths… - Journal of Allergy and …, 2004 - Elsevier
BACKGROUND: Respiratory syncytial virus (RSV) bronchiolitis in infants can lead to
wheezing and early allergic sensitization. In mice, RSV infection enhances allergic airway
inflammation and airway hyperresponsiveness. Dendritic cells are critical in inducing T-cell
responses to both viruses and allergens and could be pivotal in regulating interactions
between these. OBJECTIVE: This study addresses the effects of RSV infection on phenotype
and function of pulmonary dendritic cells. METHODS: BALB/c mice were infected with RSV …
wheezing and early allergic sensitization. In mice, RSV infection enhances allergic airway
inflammation and airway hyperresponsiveness. Dendritic cells are critical in inducing T-cell
responses to both viruses and allergens and could be pivotal in regulating interactions
between these. OBJECTIVE: This study addresses the effects of RSV infection on phenotype
and function of pulmonary dendritic cells. METHODS: BALB/c mice were infected with RSV …