Decreased pulmonary clearance of S. pneumoniae following influenza A infection in mice
AM LeVine, V Koeningsknecht, JM Stark - Journal of virological methods, 2001 - Elsevier
In children, the incidence of complicated pneumonias (including empyemas and lung
abscesses) associated with Streptococcus pneumoniae infection has increased in recent
years. In many cases, these complicated pneumonias followed flu-like illnesses. To
determine mechanisms behind this association, a murine model of sequential pulmonary
infection has been developed. BALB/cJ mice infected with influenza A had mild pulmonary
inflammation that resolved within 5–7 days. Seven days following their initial …
abscesses) associated with Streptococcus pneumoniae infection has increased in recent
years. In many cases, these complicated pneumonias followed flu-like illnesses. To
determine mechanisms behind this association, a murine model of sequential pulmonary
infection has been developed. BALB/cJ mice infected with influenza A had mild pulmonary
inflammation that resolved within 5–7 days. Seven days following their initial …