Paraneoplastic syndromes affecting the nervous system

RB Darnell, JB Posner - Seminars in oncology, 2006 - Elsevier
The paraneoplastic neurologic disorders (PND) are a diverse group of diseases
characterized by the presence of neurologic dysfunction in the setting of a remote cancer.
PND can affect almost any part of the nervous system, and are most commonly associated
with lung cancer (small cell) and gynecologic tumors. Laboratory studies have demonstrated
that an autoimmune response links the neurologic disorder and the cancer, and established
a model whereby the cancer is believed to initiate the syndrome by expressing a protein …