Microdissection of the sequence and structure of intermediate filament chains
DAD Parry - Advances in protein chemistry, 2005 - Elsevier
A large number of intermediate filament (IF) chains have now been sequenced. From these
data, it has been possible to deduce the main elements of the secondary structure,
especially those lying within the central rod domain of the molecule. These conclusions,
allied to results obtained from crosslinking studies, have shown that at least four unique but
related structures are adopted by the class of structures known generically as intermediate
filaments:(1) epidermal and reduced trichocyte keratin;(2) oxidized trichocyte keratin;(3) …
data, it has been possible to deduce the main elements of the secondary structure,
especially those lying within the central rod domain of the molecule. These conclusions,
allied to results obtained from crosslinking studies, have shown that at least four unique but
related structures are adopted by the class of structures known generically as intermediate
filaments:(1) epidermal and reduced trichocyte keratin;(2) oxidized trichocyte keratin;(3) …