Keratin 8 mutations are not associated with familial, sporadic and alcoholic pancreatitis in a population from the United States
A Schneider, J Lamb, MM Barmada, A Cuneo… - Pancreatology, 2006 - Elsevier
Abstract Background and Aims: Genetic predispositions play a major role in the
development of chronic pancreatitis. Recently, a mutation in the keratin 8 gene (G62C) was
reported to be associated with chronic pancreatitis in Italy. We determined whether
mutations in the keratin 8 gene are associated with familial, sporadic and alcoholic recurrent
acute or chronic pancreatitis in a population from the United States. Methods: We
investigated the relevant genomic region of the keratin 8 gene in 80 patients with familial …
development of chronic pancreatitis. Recently, a mutation in the keratin 8 gene (G62C) was
reported to be associated with chronic pancreatitis in Italy. We determined whether
mutations in the keratin 8 gene are associated with familial, sporadic and alcoholic recurrent
acute or chronic pancreatitis in a population from the United States. Methods: We
investigated the relevant genomic region of the keratin 8 gene in 80 patients with familial …