Glial fibrillary acidic protein in the cerebrospinal fluid of children with autism and other neuropsychiatric disorders
G Ahlsén, L Rosengren, M Belfrage, A Palm… - Biological …, 1993 - Elsevier
The cerebrospinal fluid (CSF) of 47 children and adolescents with autism was analyzed for
the contents of two astroglial proteins, the glial fibrillary acidic protein (GFA) and S 100. The
results were contrasted with those obtained in similarly aged cases with other
neuropsychiatric disorders (n= 25) and in normal children (n= 10). S-100 did not
discriminate the groups from each other. However, GFA in autism and autisticlike conditions
was at a level almost three times that in the normal group. The results could implicate gliosis …
the contents of two astroglial proteins, the glial fibrillary acidic protein (GFA) and S 100. The
results were contrasted with those obtained in similarly aged cases with other
neuropsychiatric disorders (n= 25) and in normal children (n= 10). S-100 did not
discriminate the groups from each other. However, GFA in autism and autisticlike conditions
was at a level almost three times that in the normal group. The results could implicate gliosis …