VEGF regulates FGF-2 and TGF-β1 expression in injury endothelial cells and mediates smooth muscle cells proliferation and migration
D Li, C Zhang, F Song, I Lubenec, Y Tian… - Microvascular …, 2009 - Elsevier
BACKGROUND: Vascular endothelial growth factor (VEGF) is implicated in the development
of restenosis after percutaneous transluminal coronary angioplasty (PTCA) as well as
atherosclerosis. The purpose of our study was: 1) to evaluate the expression of endothelial
cell (EC) fibroblast growth factor 2 (FGF-2) and transforming growth factor β1 (TGF-β1)
mRNA expression following vascular injury and VEGF modulation and 2) to assess whether
VEGF indirectly stimulates smooth muscle cell (SMC) migration and proliferation via growth …
of restenosis after percutaneous transluminal coronary angioplasty (PTCA) as well as
atherosclerosis. The purpose of our study was: 1) to evaluate the expression of endothelial
cell (EC) fibroblast growth factor 2 (FGF-2) and transforming growth factor β1 (TGF-β1)
mRNA expression following vascular injury and VEGF modulation and 2) to assess whether
VEGF indirectly stimulates smooth muscle cell (SMC) migration and proliferation via growth …