[PDF][PDF] Increased epidermal growth factor receptor gene copy number detected by fluorescence in situ hybridization associates with increased sensitivity to gefitinib in …
FR Hirsch, M Varella-Garcia, J McCoy, H West… - J clin oncol, 2005 - academia.edu
FR Hirsch, M Varella-Garcia, J McCoy, H West, AC Xavier, P Gumerlock, PA Bunn Jr…
J clin oncol, 2005•academia.eduPurpose Bronchioloalveolar carcinoma (BAC) and adenocarcinomas with BAC features
seem to be increasing in incidence, particularly in younger, never-smoking women.
Epidermal growth factor receptor (EGFR) inhibitors demonstrated response rates of 20% to
30% in patients with advanced BAC subtypes, but selection methods for patient therapy are
not established.
seem to be increasing in incidence, particularly in younger, never-smoking women.
Epidermal growth factor receptor (EGFR) inhibitors demonstrated response rates of 20% to
30% in patients with advanced BAC subtypes, but selection methods for patient therapy are
not established.
Purpose
Bronchioloalveolar carcinoma (BAC) and adenocarcinomas with BAC features seem to be increasing in incidence, particularly in younger, never-smoking women. Epidermal growth factor receptor (EGFR) inhibitors demonstrated response rates of 20% to 30% in patients with advanced BAC subtypes, but selection methods for patient therapy are not established.
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