Common human diseases like obesity and diabetes are driven by complex networks of
genes and any number of environmental factors. To understand this complexity in hopes of
identifying targets and developing drugs against disease, a systematic approach is required
to elucidate the genetic and environmental factors and interactions among and between
these factors, and to establish how these factors induce changes in gene networks that in
turn lead to disease. The explosion of large‐scale, high‐throughput technologies in the …