[PDF][PDF] Deregulating EMT and senescence: double impact by a single twist

MA Smit, DS Peeper - Cancer cell, 2008 - cell.com
MA Smit, DS Peeper
Cancer cell, 2008cell.com
The acquisition of a fully malignant phenotype is limited by several barriers, including
cellular senescence and the requirement to undergo an epithelial-mesenchymal transition
(EMT). Deregulation of these processes is believed to occur by largely independent events.
In this issue of Cancer Cell, Ansieau et al.(2008) challenge this view.
The acquisition of a fully malignant phenotype is limited by several barriers, including cellular senescence and the requirement to undergo an epithelial-mesenchymal transition (EMT). Deregulation of these processes is believed to occur by largely independent events. In this issue of Cancer Cell, Ansieau et al. (2008) challenge this view.
cell.com